Rethink-Revise-Customized GLP-1
Custom Formulation
Bachem Pharma GLP-1 Peptide can be customized with B12 API, Thiamine, Pyridoxine, NAD+, and L-Carnitine. FDA-registered peptides are available for rebranding and for commercial distribution with Vitamin B12-100mcg API. Manufactured with approved DMF according to the Federal Food, Drug, and Cosmetic Act. The NDC number is activated upon order.
A Custom Peptide therapy kit contains:
- 2-10ml Bacteriostatic water
- 4-Vials API Peptide
- 30cts Oral Peptide (optional)
- 1-Storage Pen
- 4-Alcohol Pads
- 4-Mixing needles
- 4-Subcutaneous pen needle
- 1-Instruction booklet
Customized GLP-1 Injection w/ Vitamin B1 (1000mcg), B6 (1000mcg),B12( 100mcg/mL), L-Carnitine (100mg), and NAD+ (20mg) plus (optional capsule form of 30cts per bottle).
Other Peptides we contract manufacture are:
- Muscle enhancement Peptides-Sermorelin
- Ipamorelin with CJC-1295 Products
- · Age reversal GHK-Cu Youth Molecule
- · Glutathione Super-antioxidant Peptide
- · Anti-inflammatory injury healing BPC-157
- · Self-enhancement and muscle growth TB-500
- · Cognitive health MOTS-C
- · Regenerative medicine NAD+
- · Skin cells renewal peptide Epitalon
Bioavailable Oral GLP-1
The addition of other minerals such as methylated forms of Vitamin B1(Thiamin), B6(Pyridoxine), NAD and vitamin B12 is intended to help to improve energy levels, boost metabolism and help burn fat, improve fatigue, muscle loss, or neuropathy—common concerns during weight loss or diabetes treatment—and may offer metabolic, neurological, and musculoskeletal benefits.
Our Customizable APIs are:
Dulaglutide
Tirzepatide
Semaglutide
Retatrutide
Cagrillintide
Exenatide
Premarketing Analytical Test
Bachem Pharma conducts extensive Pre-marketing peptide tests and analytical chemistry on all peptide entities and provides these test reports:
- Circular Dichroism Spectrometer CD analytical report that confirms the molecular structure, intermolecular interactions, and kinetic analysis of each peptide. We evaluate the secondary structure, folding and binding properties of the peptides.
- High Resolution Mass Spectrometer (HRMS) analysis report, which is more accurate and reliable, along with the Prep-HPLC purity test report. High-resolution mass spectrometry (HRMS) is an analytical chemistry technique that can distinguish between the molecular masses of compounds and provide high-resolution and high-quality mass spectral data.
- Amino Acid Analysis report. We conduct amino acid analysis on finished peptide drugs using Biochrom30+, German MembraPure A300. It is an instrument used to determine the composition or content of amino acids in proteins, peptides, and other pharmaceutical preparations.
- Comprehensive Certificate of Analysis showing details of all the test results with a full spectral peptide scan, showing the absorbance levels across the range of wavelength.
In addition to the above, we provide item reports within 30 days of order, FDA-DMF for ANDA registration or for clinical trials
Peptide and oligonucleotide synthesis (“Upstream”)
Our diverse capabilities, expert advice, and dedication to quality guarantee smooth scalability, enhanced equipment utilization, and improved efficiency throughout the production process. Collaborating with TirzPharm provides you with:
Diverse production capabilities: This includes solution-phase and solid-phase synthesis reactors, along with innovative methods such as Molecular Modifications.
Smooth scalability: Effortless scalability is achievable with solution-phase reactors reaching up to 8000 litres and solid-phase peptide synthesis (SPPS) reactors up to 500 litres. Larger options are currently under development, with a new facility in Bubendorf offering sizes up to 1000 litres.
Enhanced equipment: Rely on our GMP-qualified equipment, which includes OligoPilot synthesizers and custom-designed cleavage and deprotection equipment trains, ensuring precise control and safety when handling hazardous reagents.
Improved efficiency and quality: Our sophisticated automation and data management systems, featuring a Manufacturing Execution System and a process data historian, enhance efficiency and guarantee superior quality.
Dedication to quality: By adhering to Quality by Design principles and incorporating in-process controls and process analytical technology, we consistently achieve high-quality outcomes.
Purification and Isolation of Peptides and Oligonucleotides
Bachem Pharm is committed to the ongoing enhancement and modernization of its purification equipment to satisfy the increasing demand for bulk peptide and oligonucleotide pharmaceuticals. In addition, our team will offer you:
Advanced purification methods: Employ a variety of advanced purification techniques, such as preparative high-performance liquid chromatography (HPLC), ion exchange (IEX), size-exclusion chromatography (SEC), and ultra-filtration (UF/TFF). Scalable manufacturing: Our equipment facilitates highly efficient or continuous production of ultra-pure products in multi-kg quantities per batch.
Precise control and scalability: Dynamic axial compression (DAC) stainless steel columns with diameters of up to 60 cm guarantee optimal performance during the separation phase. Stringent microbiological control: ISO 8 and ISO 7 clean rooms equipped with HEPA-filtered air uphold rigorous microbiological control standards.
Safety measures: Down-flow booths reduce microbial contamination, and highly active pharmaceutical ingredients are managed in safety workbenches or isolators rated up to OEB level 4.
Controlled isolation: Meticulously controlled isolation processes, including precipitation, crystallization, and lyophilization of intermediates and final active pharmaceutical ingredients (API), ensure that predefined physicochemical properties are achieved. Multiple lyophilisers for quality assurance: A range of lyophilisers of different sizes ensures product integrity and quality across all batches.