FDA-Approved CMO for Biologic Drug-Device Combinations

Whether for metabolic disorders or holistic lifestyle or wellness products, Zeptide Pharma is your trusted partner in bringing innovative peptide solutions to life, the leading, innovation-driven company specializing in the development and manufacture of 506e drugs on FDA shortage lists, Insulin analogs, Biosimilars, HPLC drug purification, peptide drugs, and oligonucleotides, smoking cessation products, hair loss treatments, medical skincare products, oral solid dosages, and manufacturing of therapeutic medications and interventions.

Meeting Your Needs

Any level of purity – ranging from crude to ≥ 99.8%. Any scale – from milligrams to kilograms. Whatever your requirements may be, we create tailored solutions to meet any aliquoting needs, whether straightforward or involving lengthy, complex sequences. Furthermore, if you require your custom peptides urgently, we also offer express delivery.

The company has extensive experience and expertise across medical research, clinical development, and commercial applications, spanning pharmaceuticals and biotechnology, offering a comprehensive range of services. Operates internationally, with operations in Switzerland, Europe, the USA, and Asia.

Exactly the Tailored Peptides You Require

Fluorescent labels, multiple disulfides and stable isotopes are just some of our specialties. We offer a huge range of modifications, including N-terminal, C-terminal and backbone peptides:

Acetylation, formylation, acylation
Amidation
Biotinylation
Branched peptides
Chromogenic and fluorogenic carboxypeptidase substrates
Clickable peptides
Conjugation to polymers
Conjugation to small molecules (including imaging agents)
Cyclizations, head to tail and side chain (lactam bridge, thioether)
Dye labeled peptides
Hydrocarbon-stapled peptides
Incorporation of chelating moieties such as DOTA, DPTA
Incorporation of fluorophores or chromophores
Incorporation of D-enantiomers and unusual amino acids
Introduction of C-terminal alcohol and aldehyde moieties
Introduction of C-terminal ester and thioester groups
Labeling with stable isotopes
Labeling with Tide FluorTM and Tide QuencherTM
Ligations
Lipidation
Maleimido peptides
Methylation, alkylation
Multiple disulfide bond formation
Phosphorylation and sulfation
Retro-inverso peptides
Stabilizing modifications including PEGylation, N-methylated amino acids and reduced peptide bonds

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Higher levels of purity will require additional production efforts and time. Our recommendations are:

>95% Purity:

NMR studies
Crystallography studies
Peptides used as reference in final quantitative studies
Enzyme-substrate studies
Receptor-ligand interaction studies
Blocking and competition assays

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90-95% Purity:

Production of monoclonal antibodies
Enzyme-substrate studies (quantitative)
Receptor-ligand interaction studies (quantitative)
Blocking and competition assays
ELISA and RIA (quantitative)
In vivo/in vitro studies

>80% Purity:

Western blotting studies (non-quantitative)

Immunograde

Production of polyclonal antibodies

>65% Purity:

Determination of the titer of antibodies in standard ELISA

Why work with us?

Reliability – You’ll receive high-quality custom peptides produced by experts and checked against the highest quality standards.
Tailored service – Your requirements become our requirements: we’re built on first-rate customer service.
Innovation – We never stop looking for innovative ways to help you achieve more.
Internationally approved – Your peptides will be produced in GMP-compliant facilities, which are inspected by the FDA, EMA and Swissmedic.
Sustainability – Know that you’re improving the sustainability of your supply chain – by working with a business striving to improve its social, economic and environmental sustainability.

Custom Peptides